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العنوان
Plasma-soluble urokinase plasminogen activator receptor (suPAR) levels in behçet{u2019}s disease and correlation with disease activity /
الناشر
Arwa Osama Amin Alshaarawy ,
المؤلف
Arwa Osama Amin Alshaarawy
هيئة الاعداد
باحث / Arwa Osama Amin Alshaarawy
مشرف / Amal Hassan Rizk
مشرف / Nora Yousry Elsaid
مشرف / Walaa Abdelfattah Attia
تاريخ النشر
2018
عدد الصفحات
161 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
إعادة التأهيل
تاريخ الإجازة
9/3/2018
مكان الإجازة
جامعة القاهرة - كلية الطب - Rheumatology and Rehabilitation
الفهرس
Only 14 pages are availabe for public view

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from 175

Abstract

Background: Behçet’s disease (BD) is a chronic multisystemic vasculitic disease with unknown pathogenesis. Soluble urokinase plasminogen activator receptor (suPAR), a potential new biomarker, is a soluble form of membrane-bound receptors secreted from different immune cells.The Aim of the present study is to investigate plasma suPAR levels in Behçet’s disease and their correlation with disease activity.Patients and Methods: Fifty Adult Behçet’s disease patients determined according to the BD International Study group criteria for Behçet’s disease diagnosis and Fourty Adult healthy subjects were included in the present study. Enzyme-linked immunosorbent assay was employed to obtain quantitative data. Data of both groups were statistically analyzed.Results: The suPAR level was not statistically different between the Behçet{u2019}s disease patients and controls. For Behçet{u2019}s patients mean was of 0.2±0.5ng/mL compared to a mean of 0.3±0.4ng/mL for controls. P value was 0.413.This cross-sectional study showed that suPAR does not have any significant relation with disease activity in BD patients