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Abstract Diabetic macular ischemia (DMI) is a condition that didn’t receive enough attention despite its important impact. The presence of DMI in the context of diabetic retinopathy and maculopathy affects visual acuity and changes management decisions. FFA is – so far - the gold standard for diagnosis and grading of DMI, It was used in this study as a method of patients enrollment. However, FFA has its hazards and drawbacks especially being invasive, non-repeatable, difficult data quantification and that associated leakage can obscure the presence of ischemia. OCTA may provide images with higher details regarding macular status, becoming a novel imaging technique for the diagnosis of DMI, and may become an alternative to FA for this purpose. It is capable of imaging the two major layers of the retinal vasculature without dye injection. |