الفهرس 
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Abstract
This study was carried out to investigate the effect of maxillary obturators lined with silicon based soft relining material and acrylic based soft relining on the accumulation of oral floral among patients with lateral maxillectomy defect by assessing the total microbial count and bacterial DNA load detection by Real-time PCR. Two commercially available silicon based soft relining material ’’Multisil-Soft ’’ and acrylic based soft relining material ’’ COE-SOFTTM ’’ were selected for their biological evaluation.
Fourteen patients with lateral maxillectomy defect were precisely selected and thoroughly examined in an attempt to reduce human variables and eliminate any factor or habit that might adversely affect the results of this study.
All patients were rehabilitated with definitive hollow obturator constructed from heat cured acrylic resin. After one month adaptation period, patients were recalled for relining of the obturator.
Patients were randomly divided into two equal groups according to the relining material.
• group I: Definite obturator for patients of this group was relined using silicon based soft relining material.
• group II: Definite obturator for patients of this group was relined using acrylic based soft relining material.
For all patients, microbiological samples were taken for bacterial count and bacterial DNA load detection by Real-time PCR. Microbial evaluation was performed at the time of relining, three and six months after relining of the obturator. Data were tabulated and statistically analyzed.
- The results obtained from this study revealed
Samples obtained after relining of the acrylic obturators exhibited marked decrease in bacterial count and increase in bacterial DNA load.
Marked decrease in bacterial count and increase in bacterial DNA load in patients rehabilitated with the obturators lined with silicon based relining material (Multisil-Soft) compared to acrylic based soft relining material (COE-SOFT)TM.
Results obtained from this study showed that there was marked decrease in bacterial count and increased in bacterial DNA load after six months for both groups of the relining of the obturator.
Within the limitations of this study, the following could be concluded:
Acrylic based relining material (COE-SOFTTM) is more heavily accumulation of oral floral than silicon based relining material (Multisil-Soft).