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Abstract ABSTRACT Background: Vitamin D has assorted immunomodulatory, calming, cell reinforcement, and hostile to fibrotic activities, that have justified its thought as a basic pathogenic figure the event and seriousness of different invulnerable intervened infections, including immune system hepatitis. Objective: He point of the review is to survey serum levels of 25(OH) D in kids and teenagers with AIH, assess the relationship between serum 25(OH) D levels and clinical, histological, biochemical highlights of AIH and to assess the relationship between serum 25(OH) D levels and reaction to immunosuppressive treatment. Methods: This controlled cross sectional review was performed on a sum of 30 kids and immaturities determined to have immune system hepatitis following up in Pediatric Hepatology Clinic, Faculty of Medicine, Ain Shams University. They were 13 guys and 17 females, their age went from 5-17 years of age and 15 age and sex matched kids as control bunch beginning from October 2021 till July 2022. Results: Conclusion: As apparent from the ongoing review, severe vitamin D lack happens in patients with AIH. Interface hepatitis was seen as in 93.3%, connecting fibrosis in 86.7% and lymphocytic penetration in 80% in the event that gathering of immune system hepatitis. Stomach expansion is the most well-known side effect in liver sickness (46.7%) trailed by right hypochondrial torment (26.7%). |