الفهرس 
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Abstract
Heterocycles are abundantly distributed in nature and they play a vital role in the metabolism of living cells. They have contributed widely to understand and improve the quality of life processes. Presently, the majority of the published work in crystallography involves at least one heterocyclic ring Nowadays, bioinorganic chemists target the heterocyclic ligands and their metal complexes to study their pharmacology as the main focus of research [11]. A wide range of biological activities [12-14] such as antibacterial, antifungal, antitumor and antiviral activities are exhibited by the nitrogen-containing organic compounds and their metal complexes. Transition metal complexes offer two distinct advantages as DNA-binding agents [15]. First, transition metal centres are particularly attractive moieties for reversible recognition of nucleic acids research because they exhibit well-defined coordination geometries. Besides, they often show distinct electrochemical or photophysical properties, thereby increasing the functionality of the binding agent [16]. According to these smart features, the complexes can be used in a broad spectrum of applications, from fluorescent markers to D.N.A. foot printing agents, to electrochemical probes [17]. Transition metals exhibit different oxidation states and can interact with several negatively charged molecules. The integration of metal with the organic compound can produce well-diversified structures with pronounced biological activities due to chelation.