الفهرس 
RESULTSOnly 14 pages are availabe for public view
 |  | from | 175 |  |  |
| | | from | 175 | | |
Abstract
New Remineralization therapies aim to improve the existing fluoride treatments rather than replacing them, fluoridated miswak varnish was proven to have remarkable antimicrobial and remineralizing potentials on primary teeth in experimental studies.
Study objective: To evaluate the remineralizing effect of fluoridated miswak varnish on initial caries-like lesions in permanent teeth compared to fluoride varnish (DURAPHAT) through surface microhardness analysis and polarized light microscopy evaluation.
Materials and methods: Forty four premolars were selected, coated with nail varnish, except for standardized 4x4 mm buccal enamel windows. Each tooth was sectioned into two halves buccolingually, giving mesial and distal halves. One half was treated with the varnish to be tested and the other half remained untreated serving as its negative control. Specimens were immersed in the demineralizing solution for 96 hours to produce artificial carious lesions. The study sample (88 specimens) were randomly assigned into two groups according to the treatment agent; group I (fluoridated miswak varnish), group II (Duraphat varnish). Specimens were evaluated both quantitatively and qualitatively. from each group, half of the specimens and their corresponding controls were examined with Vickers Microhardness Device. Enamel surface microhardness was measured at baseline, after demineralization and after treatment. While the remaining specimens were prepared and analyzed using Polarized Light Microscopy for evaluating changes in enamel birefringence.
Results: Both groups demonstrated a statistically significant increase in enamel surface microhardness compared to their controls (P<0.0001). As for Polarized Light Microscopy, both groups; fluoridated miswak and Duraphat, showed a statistically significant increase in the negative birefringence (P=0.047), (p=0.003) respectively. By comparing both test groups, there was no statistically significant difference in mean percent recovery of microhardness and mean lesion depth percent reduction (P=0.088), (P=0.949) respectively.
Conclusion: Both fluoridated miswak and Duraphat varnishes had comparable remineralizing potential on initial caries-like lesions in permanent teeth. However, Duraphat varnish was more effective in remineralizing the lesion body.