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العنوان
Hematological markers and ultrasound 7-joint inflammation score as add on tools in assessment of inflammation in rheumatoid arthritis patients/
المؤلف
Hanafi, Maha Saeid Mahmoud.
هيئة الاعداد
مشرف / عبد اللطيف أحمد جاب الله
مشرف / نهى عبد الحليم الصاوى
مشرف / وسام محمد الجندى
مشرف / أحمد حافظ عفيفى
الموضوع
Physical Medicine. Rheumatology. Rehabilitation.
تاريخ النشر
2022.
عدد الصفحات
111 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
إعادة التأهيل
تاريخ الإجازة
21/8/2022
مكان الإجازة
جامعة الاسكندريه - كلية الطب - Department of Physical Medicine,Rheumatology and Rehabilitation
الفهرس
Only 14 pages are availabe for public view

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from 128

Abstract

Rheumatoid arthritis (RA) is an autoimmune disease that causes joint destruction and synovial inflammation, eventually leading to severe disability. The etiology of RA is a complicated process including genetic and environmental factors, which results in a chain of events leading to synovitis, cartilage damage, and subchondral bone loss.
Changes in the amount and composition of circulating blood cells are linked to systemic inflammation. As a result, the characteristics of circulating blood cell components can be utilized to evaluate inflammatory activity.
The neutrophil-to-lymphocyte ratio, PLR, MPV, PDW and RDW have all been studied as inflammatory markers in a variety of inflammatory, cardiovascular, and malignant diseases.
These markers are inexpensive and readily available. The results of comparing their blood levels in RA patients to normal people, as well as their relation to RA disease activity, were equivocal.
In rheumatology practice, ultrasound is frequently used. The Ultrasound 7 score is a reproducible ultrasound scoring system for RA and other inflammatory arthropathies.
The aim of the present study was to correlate the hematological markers and ultrasound 7-joint inflammation score with disease activity in rheumatoid arthritis patients.
A total of 54 RA patients were included in the study, all of them were diagnosed using the 2010 ACR/EULAR diagnostic criteria. The research excluded patients with inflammatory arthropathies, cancer, acute or chronic infection, chronic granulomatous disease, being pregnant or shortly post-partum, and those with renal disease. The study included thirty healthy control subjects with matching age, sex and general constitution as a control group.