الفهرس 
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Abstract
Summary
Cerebral microbleeds are a prevalent, age-related disease affecting the small blood vessels of the brain. CMBs are small and rounded hypointense lesions seen on magnetic resonance imaging (MRI), are considered one kind of biomarker of SVD. So far, the clinical implications of CMBs have not been examined in different neurological disorders.
The aim of this study was to investigate the ability of Susceptibility Weighted Imaging (SWI) to detect cerebral microbleeds in elderly and to correlate such microbleeds with the cognitive function.
This observational cross-sectional study was performed on 58 elderly subjects above the age of 50. Cognitive functions for the included subjects were assessed using Paced Auditory Serial Addition Test (PASAT), Benton Visual Retention test (BVRT) and Paired Associate Learning test (PALT). All included subjects underwent routine magnetic resonance Imaging (MRI) and susceptibility weighted images (SWI).
The mean age of the studied participants was 66.5±8.4 years. There were 63.8% males among the participants and 36.2% females.
Our study showed that, there were statistically significant negative correlations between cognitive functions assessed by the scores of PALT, BVRT, PASAT, and lobar microbleeds and total number of microbleeds. In addition, there was a statistically significant negative correlation between PASAT score and number of infra-tentorial microbleeds.
Also, there were statistically significant positive correlations between Fazekas grades and the number of infra-tentorial and deep microbleeds in addition to the total number of microbleeds.
There were no statistically significant correlations between age and number of microbleeds in either infra-tentorial, deep, lobar regions or the total number of microbleeds. Male subjects had a significantly higher number of microbleeds than females in infratentorial and lobar regions in addition to the total number of microbleeds.
There were no statistically significant differences between subjects with and without diabetes regarding the number of microbleeds in all brain regions. However, the occurrence of microbleeds is still higher in diabetic patients than non-diabetic patients. Also, there were no statistically significant differences between subjects with and without hypertension regarding the number of microbleeds in all brain regions. However, the occurrence of microbleeds is still higher in hypertensive patients than non-hypertensive patients in all brain regions except the infra-tentorial region.