الفهرس 
Anatomy of Cornea
Infectious KeratitisOnly 14 pages are availabe for public view
 |  | from | 133 |  |  |
| | | from | 133 | | |
Abstract
Infectious keratitis is a major sight threatening disease that may lead to blindness so proper diagnosis and early treatment is very important to prevent vision loss and preserve globe. Infectious keratitis resistant to medical treatment is remaining challenging, Therfore surgical intervention is sometimes needed to promote healing and prevent corneal perforation. The amniotic membrane (AM), a thin membrane on the inner side of the placenta, is recently recognized as an effective tool in management of resistant infectious keratitis as it can suppress inflamation , promote healing, restore integrity of the ocular epithelium and prevent corneal perforation. The aim of our study is to evaluate effectivness and safety of single versus double layer amniotic membrane transplantation in management of resistant infectious keratitis. This study was carried out on forty eyes with resistant infectious keratitis as diagnosed clinically and confirmed by culture and sensitivity of patients attended outpatient clinic and the cornea unit of ophthalmology department at Tanta University. They were divided into two groups: in group A patients were managed by single layer AMT while in group B they were managed by double layer AMT. The current study showed no statistically significant differences between two groups in healing time and visual improvement postoperatively as healing was achieved in time range 3-8 weeks ingroup A while in group B it range 3-6 weeks and visual acuity remain unchanged in most of cases in both groups. The current study showed statistically significant difference between two groups in healing of sever corneal ulcer as in group A all cases with sever corneal ulcer showed failure of healing while in group B successful healing was achieved in 83.33% of cases. But it showed no significant difference between two groups in healing of mild .and moderate corneal ulcer