الفهرس 
Implantable cardiac device infections prevalence : Diagnostic and therapeutic implications
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Abstract
Background: The use of cardiac implantable electronic device (CIED) [permanent pacemakers, implantable cardioverter-defibrillators (ICD), cardiac re-synchronized therapy (CRT)], have been shown to improve mortality and quality of life in many different patient populations. Moreover, implantation rates have increased throughout the last several decades. CIED related infection is a serious complication with significant morbidity and mortality. Objectives: We sought to evaluate the prevalence of CIED related infection as well as time of onset of infection from the last device manipulation, risk factors, clinical and demographic characteristics, causative organisms and the management and outcome of patients presented in the Critical Care Department, Cairo University. Methods: A retrospective analysis was conducted of 1871 patients who had undergone cardiac device implantation with total number of devices of 1968 and 2270 procedures performed from January 2007 to December 2017. Results: Among 1871 patients we identified 59 infectious episodes with an estimated incidence of 2.99% of totally inserted devices and 2.6% of total procedures. The infection rate in patients who had undergone recurrent procedures was significantly higher than in patients a single procedure (9.27% vs. 1.18%; P<0.001). Patients with dual chamber ICD and CRTD had the highest infection rate of 6.25% & 6.85% respectively. Pocket infection was identified in 35 cases and CIED related endocarditis (CDE) was identified in 24 cases with an incidence in relation to total procedures of 1.54% & 1.06% respectively