الفهرس 
Comparative study between combined vaginal Misoprostol with Isosorbide-5-Mononitrate versus Misoprostol alone for Induction of the second trimesteric missed abortion
Table of ContentsOnly 14 pages are availabe for public view
 |  | from | 107 |  |  |
| | | from | 107 | | |
Abstract
To compare the therapeutic efficacy of prostaglandins when they are used alone versus a combination therapy of prostaglandins and a nitric oxide (NO) donor as isosorbide-5-mononitrate to induce cervical ripening and effacement for induction of the second trimester missed abortion and occurrence of complete abortion.METHODS:A Randomized clinical trial study in which 160 Second trimester (13-26 weeks) missed abortion pregnant women admitted for medical induction of abortion, were randomly divided into two group ( 80 patients in each ). One group received only vaginal Misoprostol and the other group received combined vaginal Misoprostol with Isosorbide-5-mononitrate.To determine the efficacy in form of ” induction abortion interval ”: the duration interval between the beginning of the induction and the complete expulsion of the abortus and also the number of the doses of misoprostol needed to complete expulsion and also the adverse events that increased or newly discovered when prostaglandins and a nitric oxide donor used together such as severe bleeding , headache, abdominal pain, pelvic pain,severe hypotension,backache, fever, nausea and vomiting