الفهرس 
Quantitative dynamic contrast enhanced MRI and diffusion-weighted imaging in assessment of chemotherapy treatment response of osteosarcoma and ewing sarcomab
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Abstract
Introduction Osteosarcoma and Ewing{u2019}s sarcoma family of tumors is an aggressive form of childhood cancer. Evaluation of multi-parametric MRI using quantitative DWI and DCE-MRI in predicting chemotherapy response in pathologically proven cases of osteosarcoma & Ewing{u2019}s sarcoma with correlation between the tumor size changes & internal breakdown using RECIST 1.1, modified RECIST & tumor volume.aim of the work Analysis of the value of dynamic contrast-enhanced MRI in some cases and DWI in comparison to conventional MRI sequences in the initial evaluation and post-chemotherapy follow up the response of pathologically documented cases of osteosarcoma and Ewing sarcomas.Patients and Methods The study included 104 patients pathologically proved osteosarcoma (53 patients) & Ewing`s sarcoma (51 patients) underwent MRI examinations; prior to & after chemotherapy. All patients were assessed using the RECIST 1.1 criteria, m-RECIST, quantitative ADC & tumor volume evaluation. Correlation between the different evaluations was done. Results were correlated with the postoperative pathology in 42 patients underwent surgery & for statistical evaluation, these patients were classified into responders ({u2265}90 % necrosis) & non-responders (<90 % necrosis)