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Abstract Background: Primary percutaneous coronary intervention (PCI) is the preferred reperfusion strategy in ST-elevation myocardial infarction (STEMI), Immediate transfer for early angioplasty after thrombolytic therapy has been shown to improve outcome compared with thrombolysis alone.TIMI myocardial perfusion (TMP) grade provides important prognostic information beyond epicardial flow.The importance of myocardial reperfusion in STEMI patients treated by thrombolysis followed by early PCI been assessed by left ventriculography and final infarct size by perfusion study is studied. Aim: To assess the association between TIMI myocardial perfusion (TMP) at the end of the PCI procedure and left ventricular function (LVEF) and infarct size within one month in such patients Materials And Methods: A total of 40 patients with STEMI (mean age 57.32 ± 10.44, 33 men) were studied, All patients underwent 1ry PCI. Grading of myocardial perfusion is done during PCI. Infarction size, EDV, ESV and EF were estimated by myocardial perfusion (Gated SPECT) imaging within one month from STEMI |