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العنوان
CD44 Expression in Egyptian Patients with Acute Myeloid
Leukemia
الناشر
Genetic Engineering and Biotechnology Research Institute
المؤلف
Mohamed Hanan Abdalla Elshabrawi
هيئة الاعداد
باحث / Hanan Abdalla Elshabrawi Mohamed
مشرف / Samir Ali Mohamed El-Masry
مشرف / Salah Elshahhat Aref Elgendy
مشرف / Kadry Abd Elkader Mokhtar Elbakry
الموضوع
Leukemia
تاريخ النشر
2022
عدد الصفحات
164,P
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض الدم
تاريخ الإجازة
1/1/2022
مكان الإجازة
جامعة مدينة السادات - معهد بحوث الهندسة الوراثية - Biochemistry and Molecular Biology
الفهرس
Only 14 pages are availabe for public view

from 164

from 164

Abstract

Cancer is an aggressive disease involving abnormal cell growth with the
potential to invade other parts of the body through the blood or the lymph
system. Acute myeloid leukemia (AML) is a form of cancer originated from
malignant clonal stem cells in bone marrow marked by heterogenous clinical
outcome due to the complexity of its molecular and cytogenetic architecture.
In these regard, Gene mutations and chromosomal abnormalities are usually
associated with aberrant proliferation and/or block in the normal
differentiation of hematopoietic cells. So far, the combination of cytogenetic
profiling and molecular and gene mutation analyses remains an essential tool
for the classification, diagnosis, and treatment for AML.