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Abstract Background:Lumbar cortical bone trajectory (CBT) screw constructs provide an alternative method of pedicle screw (PS) in lumbar spine fixation and fusion. It follows an inferior to superior pathway in the sagittal plane and a medial to lateral pathway in the transverse plane. Aim of the study: to evaluate efficacy of CBT as compared to traditional PS in lumbar spine fixation as regards clinical, radiological, surgical outcomes, fusion rate and complications. Materials and Methods:In total, 40 patients with lumbar spine pathologies requiring fixation were enrolled in this prospective study and divided into 2 groups: group A (20 patients)were fixed by CBTs, andgroup B (20 patients) were fixed using PS.Clinical ((ODI) and (VAS) scores), radiological, surgical outcomes, fusion rate and complications were evaluated and compared prospectively between both groups. Results:According to our study, CBT technique provided similar clinical outcomes (VAS, ODI), fusion rates, complications (intraoperative, postoperative), and operation time and hospital stay, compared to PS technique in lumbar fusion surgery. However, CBT technique provided the additional benefits of less blood loss but has the drawback of more radiation exposure.We noticed thatCBTs has inferior results to PS in cases of fracture lumbar spine regarding maintenance of correction achieved on the follow up period |