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العنوان
Comparative study between digital subtraction angiography (DSA) and dual-phase cone beam computed tomography (DP-CBCT) in trans-arterial chemo-embolization (TACE) in patients with hepato-cellular carcinoma (HCC) /
الناشر
Ahmed Shawky Ali Farag ,
المؤلف
Ahmed Shawky Ali Farag
هيئة الاعداد
باحث / Ahmed Shawky Ali Farag
مشرف / Ahmed Hosni Kamel
مشرف / Mohamed Mahmoud Nabil
مشرف / Mohammed Hamadna Allah Elghobashy
تاريخ النشر
2021
عدد الصفحات
104 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
12/4/2020
مكان الإجازة
جامعة القاهرة - كلية الطب - Radio- Diagnosis
الفهرس
Only 14 pages are availabe for public view

from 130

from 130

Abstract

One of the keys to successful TACE lies in seeing and reaching tumor lesions after accurate and comprehensive assessment of all feeding arteries. Conventionally, operators rely on fluoroscopy and digital subtraction angiography (DSA). However, the intrinsic two-dimensional nature of DSA and its low contrast resolution limit tumor detection, resulting in a recent adoption of intraprocedural cone-beam computed tomography (CBCT) for its axial and three-dimensional (3D) volumetric visualization, as well as superior soft tissue sensitivity. Utilizing CBCT images during interventional procedures bridges the gap between the world of diagnostic imaging (typically three-dimensional imaging but performed separately from the procedure) and that of interventional radiology (typically twodimensional imaging). Purpose To investigate the impact of dual phase-cone beam computed tomography (DPCBCT)- based navigation imaging during transarterial chemoembolization (TACE) of hepatocellular carcinoma (HCC) regarding the tumor detectability, tumor-feeding vessel visibility and superselective embolization in TACE compared to DSA . As well as intra-procedure assessmemt of tumor respone compared to follow up triphasic CT/MRI . Materials and Methods This perspective study includes 100 adult patients (51 males & 49 females, mean age, 62.7 years ± 7.19 [standard deviation]{u2013} 64 first-time TACE) with the diagnosis of HCC (confirmed eitherhistologically or by the typical features of HCC ) who underwent TACE using three-dimensional image guidance with automatic detection of tumor-feeding vessels computed from DP-CBCT (early and delayed arterial phases)