الفهرس 
Title : Cervical and Ocular Vestibular Evoked Myogenic Potential in Central Vestibular Disorders
AbstractOnly 14 pages are availabe for public view
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Abstract
Background: Causes of central vertigo include Cerebrovascular Disorders, Migraine and Multiple Sclerosis. In migraine and MS, a gross structural lesion may not be detected on magnetic resonance imaging (MRI) in patients with true vertigo. There is a need to detect the potential dysfunction in the vestibular pathway in those conditions via neurophysiological methods. Objective: This study aims at functional evaluation of the findings of cervical Vestibular-evoked myogenic potential (cVEMP) and ocular VEMP (oVEMP) in patients with migraine and MS, as examples of central vestibular disorders, and assessment of the utility of these tests in detection and localization of the related vestibular dysfunction. Subjects and methods: A cross-sectional study including 90 subjects divided into 3 groups: (1): 20 Migraine patients, (2): 40 MS patients, and (3): 30 healthy subjects who were sex and age matched. All participants were subjected to: History taking, otological examination, basic audiological evaluation, bedside examination for the dizzy patient, cVEMP, oVEMP, computerized dynamic posturography (CPD), subjective visual vertical and video-nystagmography tests. Results: clinical data: 12 patients (60%) of migraine patients had vertigo and 22 patients (55%) of MS patients had vertigo. Migraine patients showed delayed cVEMP latency in 35% of patients, as well as abnormal oVEMP in 40%, in the form of statistically significant delayed right oVEMP P1 and left oVEMP N1 latency compared with controls (p-values 0.050 and 0.038 respectively). MS patients had abnormal cVEMP responses in 37.5% in the form of statistically significant delayed left cVEMP P13 latency and Lt cVEMP N23 latency, compared with controls (p-values 0.008 and 0.038 respectively). oVEMP was abnormal in 67.5% of MS patients, with statistically significant delayed right oVEMP N1 and P1 latencies and smaller rectified N1-P1 amplitude, compared with controls (p-values 0.002; 0.012; and 0.000 respectively)