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Abstract This study was conducted to compare between efficacy of negative pressure therapy versus polarized light therapy on chronic wound healing . Thirty patients diagnosed clinically by physician as chronic wounds.They suffered from grade 2 & 3 ulcers based on clinical investigations. Their age ranged from 45 to 65 years. They were assigned randomly into two groups (A, B) equal in number. group A received negative pressure therapy with dressing changes 3 times per week in addition to their medical treatment for 6 weeks. While, group B received 10 min polarized light Therapy 3 times per week in addition to their medical treatment for 6 weeks.Wounds were evaluated by tracing paper , volumetric assessment before and after 3 weeks and 6 weeks . The results of this study revealed that there was a statistically highly significant decrease in mean value of wound surface area and volume of group (A) when compared with its corresponding value in group (B): , it could be concluded that negative pressure therapy was an effective method in chronic wound healing more than polarized light therapy |