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العنوان
Electrochemical performance of modified carbon sensors for potentiometric determination of some drugs in pharmaceutical formulations /
الناشر
Maysa Ramadan Moustafa Mohammed ,
المؤلف
Maysa Ramadan Moustafa Mohammed
هيئة الاعداد
باحث / Maysa Ramadan Moustafa Mohammed
مشرف / Eman Yossri Zaki ,
مشرف / Marwa Elbadry Mohamed ,
مشرف / Khaled M. Ismail
تاريخ النشر
2021
عدد الصفحات
109 P . :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
كيمياء المواد
تاريخ الإجازة
17/10/2020
مكان الإجازة
جامعة القاهرة - كلية العلوم - Analytical Chemistry
الفهرس
Only 14 pages are availabe for public view

from 125

from 125

Abstract

In this work, the construction and performance characteristics of new sensitive and selective modified carbon paste (MCPE) and screen printed (MSPE) potentiometric sensors modified with different ion pair were described for the determination of antispasmodic drug (Oxybutynine HCl) in pure form, biological fluids and pharmaceutical preparations. Many of experimental parameters affecting electrode efficiency were investigated, such as the effect of plasticizer, ion pair type, ion pair content, response time, temperature, effect of pH on the proposed electrodes. Studying of the interfering ions by studying the selectivity behavior of the proposed electrodes .Validation parameters were studied like linearity, accuracy, precision, limit of detection, limit of quantification and specificity