الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Results obtained here are of relevance for clinical decision making in the ongoing COVID-19 pandemic, increased levels of interleukin-6 and the occurrence of a cytokine storm are an important predictor of disease severity in affected patients. Also, our systematic review and has shown that lower serum concentrations of C3 and C4, indicating excessive complement activation and product consumption, are significantly associated with the presence of severe disease and increased mortality in patients with COVID-19. This study aimed to assess the severity of the disease in COVID-19 patients by investigation of cytokines and complement level. The results of blood showed : Blood samples of 90 patient’s males and females infected with COVID-19. Most of cases were severe cases (61.1%) followed by moderate (20%) and critically ill cases (18.8%). The characteristics of studied COVID-19 cases revealed that there was no statistically significant difference between severity groups as regards age and sex. Hematological findings of studied COVID-19 patients showed that average white blood cells and lymphocytic count and platelets count and hemoglobin were lower in critically ill patients than sever. However, neutrophil percentages were higher in critically ill patients. In general, there was no statistically significant difference between hematological findings in different groups (p>0.05) PH and oxygen saturation of studied COVID-19 patients shows that there was statistically significant difference between moderate and critically ill COVID cases as regards PH (p0.05). Also, there was statistically significant difference between severe and critically ill COVID cases (p0.05) as regards PH. On the contrary, there was no statistically significant difference between groups as regards the oxygen saturation (p>0.05) C Reactive Protein Inflammatory marker of studied COVID-19 patients shows that there was no statistically significant difference between groups as regards CRP. Liver enzymes of studied COVID-19 patients show that there was statistically significant difference between critically ill and moderate group as regards the (AST) levels (p0.05) However, there was no statistically significant difference between severity groups as regards average levels of (ALT) and Alkaline phosphatase and Sr. Albumin (p>0.05) `The median alkaline phosphatase level showed that was higher among critically ill cases than severe and moderate cases Coagulation profile according to severity of COVID-19 shows that there were no statistically significant differences between severity groups as regards prothrombin time and INR with tendency to higher mean levels among critically ill cases. Kidney function among studied COVID-19 cases shows that there was no statistically significant difference between severity groups as regards serum creatinine levels. Immunological markers of studied COVID-19 patients shows that average interleukin-6 were higher in critical than sever, however.