الفهرس 
C orona virusOnly 14 pages are availabe for public view
 |  | from | 191 |  |  |
| | | from | 191 | | |
Abstract
ABSTRACT
Background: The high prevalence of diabetes globally makes it a frequent comorbidity in patients with coronavirus-associated disease 2019 (COVID-19. As diabetes increases the susceptibility to different kinds of respiratory infections, is often identified as an independent risk factor for developing lower respiratory tract infections
Aim of work: This study aims to describe the glycemic characteristics and clinical outcomes in a sample of Egyptian COVID-19 patients with or without diabetes.
Patients and Methods: A cross-sectional study performed on 160 patients in chest out-patient clinic of kafr el sheikh chest hospital and will be divided to 2 groups: 80 diabetic patients with covid-19 and non-diabetic patients with covid-19. All candidates were subjects to full history, laboratory investigations (Fasting blood glucose, 2hrs post prandial, HbA1c, RT-PCR, CRP, D-dimer, Serum ferritin, Serum cholesterol, Serum Urea, Serum creatinine, SGOT, SGPT, Oxygen saturation by pulse oximetry & acetone in urine and Evaluation of the clinical outcome of the patient after COVID-19 infection whether recovery after home isolation and treatment, hospitalization in isolation hospitals, or ICU admission.
Results: Statistically significant higher in Diabetic than non-Diabetic covid -19 patients regarding Age, BMI, Chest CT and Prognosis, D-dimer(mg/l), S. Ferritin, CRP, O2 saturation, SGOT, SGPT, S. cholesterol, S. urea, S. creatinine and DKA/HHS. Age, BMI, D-dimer, S. Ferritin, CRP, SGOT, SGPT, S. cholesterol, S.urea and S. creatinine are positively correlated with FBG while O2 saturation is negatively correlated with FBG. A highly statistically significant difference found between home treated, hospital admitted and ICU admitted groups regarding Age, BMI, Chest CT, PCR, FBG, 2HPP, D-dimer (mg/l), S. Ferritin (0-300ng/ml), CRP, O2 saturation, SGOT, SGPT, S. cholesterol, S.urea, S. creatinine and DKA/HHS being higher I ICU admitted followed by hospital admitted then home treated patients. Chest CT findings severity, O2 Saturation, Serum ferritin, CRP and D.dimer are highly sensitive predictors of need for ICU admission. Serum ferritin was the most predictive factor for ICU admission. 2
Conclussions: Diabetic patients are more susceptible to severe COVID-19 infection, and show higher levels of inflammatory markers and systemic affection as liver functions, kidney functions and serum cholesterol. Chest CT findings severity, O2 Saturation, Serum ferritin, CRP and D.dimer are highly sensitive predictors of need for ICU admission..