الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Crohn’s disease is a chronic inflammation of the gastrointestinal tract which is immune
mediated and relapsing and remittent in behavior affecting GI tract from mouth to anus in a
patchy manner. It is a result of genetic and immune and environmental factors that interact
together to form this pattern of inflammation.
Ulcerative Colitis is a chronic inflammation of the colon which is immune mediated and
relapsing and remittent in behavior affecting only the mucosa of the colon in a continuous
manner. It is also formed because of interaction between genetic, immune, and environmental
factors.
Gut microbiome is a collection of different types of commensal bacteria that live in the
mucosa of the GI tract and have some beneficial functions to the body and harmful functions.
If the normal balance of these bacteria is maintained, there will not be any disease. But, if this
balance is disturbed, there will be a disease, and this disturbance is called “Dysbiosis”.
This study was conducted to identify this dysbiosis changes in the two diseases in
relation to the normal persons to use it as marker to differentiate the two diseases and to use it
in treatment strategy for these diseases.