الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Uterine fibroid are benign smooth muscle tumors of the uterus. They are the most common benign pelvic tumors among women in reproductive age group and are not observed in pre-pubescent girls, indicating that tumor origin depends on hormonal changes. They are clinically diagnosed in 20- 30 % of women and established at autopsy in an additional 20-30. The origin of UFs is multifactorial and its exact pathophysiology is still unknown. The known underlined risk factors which increase the incidence of UF are: black race, elevated body mass index (BMI), age, positive family history, early menarche, hypertension, time elapsed since last labor, diet containing high amount of red meat. In recent years, significant progress has been made in understanding the basic mechanism of initiation and development of leiomyoma. Fibroids vary greatly in size, location, and symptoms. Most tumors are largely asymptomatic, but they may also cause a wide range of severe and chronic symptoms in approximately one-quarter to one-third of the affected women. The most common symptoms include abnormal and excessive uterine bleeding, secondary iron deficiency anemia, abdominal and pelvic disorders like bloating and constipation. Fibroids are the most common indications for hysterectomy, they are identified 77% of the patients who have undergone this procedure. The aim of the study was to investigate the association between vitamin D status and uterine fibroid. This conducted on 75 women in their reproductive age (20-45yrs). They were divided into two groups. 50 women with at least one uterine fibroid with a diameter less than 5 cm (Small), equal or more than 5 cm (Large) detected by transvaginal ultrasound to be considered as case group women and the other 25 women with normal uterine examination and Pelvic ultrasound representing the control group.