الفهرس 
Aim of the studyOnly 14 pages are availabe for public view
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Abstract
Objective: This study was conducted to assess chemerien level and
detect its role as a predictor for gestational diabetes mellitus by
studying the relation between serum chemerin level in the first
trimester and development of GDM.
Background: Chemerin is an adipokine that regulate adipocyte
development and metabolic function as well as glucose metabolism in
liver and skeletal muscle tissue. Gestational diabetes mellitus (GDM)
is defined as glucose intolerance first recognition during pregnancy.
The incidence of GDM is increasing year by year all over the world,
especially in developing countries.
Patients and Methods: This Case control study has been conducted
on atotal number of 162 patients, divided into two groups according to
their BMI: group 1: normal weight group 2: Overweight, marked or
morbid obese. Participants were selected from those attending
obstetrics and Gynecology outpatient clinic Birket Al Sabaa hospital.
Results: Based on past review of literature that assumed the
prevalence of gestational diabetes to be (13.2%) sample size has been
calculated and it will be 162 patients. Based on the current results
gestational diabetes was diagnosed among 12.3% (20 patients),
randomly 80 patients were chosen out of 142 free gestational diabetes
ones to further analyze the data.
Conclusions: Based on the results of the present study, we conclude
that Serum chemerin level during the first trimester of pregnancy has
potential to predict risk of GDM. The meta-analysis support chemirin
as a novel biomarker for the early diagnosis of GDM, which affect
many pregnant women.