الفهرس 
TitleOnly 14 pages are availabe for public view
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Abstract
Urinary tract infections (UTIs) are among the most prevalent community and hospital
bacterial diseases. In Alexandria there are no studies about the risk factors of antimicrobial
resistance in urinary tract infections. The objective of the study is to identify the prevalence of
antimicrobial resistance and to determine the factors associated with antimicrobial resistance
among pathogens causing urinary tract infections at urology department.
The study design was an observational retrospective record- based study. This study
was conducted in the Urology department, Alexandria University Hospital from October 2018
to October 2020. Clinical, laboratory, radiology, and microbiology data from medical records
were collected. Multivariate logistic regression model was used to assess risk factors
associated with antimicrobial resistance.
The total number of patients recruited in the study was 1091( 622 Patients without
urinary tract infections, 206 patients with community acquired UTI, and 263 patients with
hospital acquired UTI). Females have a higher prevalence of UTIs.
The most common organisms isolated from the cultures were E. coli, followed by
Klebsiella pneumonia, Proteus mirabilis, and Pseudomonas aeruginosa. The resistant cultures
(MDR,XDR,PDR) were 300(77.3%), while the sensitive cultures were 88(22.7%). Antibiotic
resistance rates were greater in hospital-acquired UTIs than in community acquired UTI.
Summary, Conclusions and Recommendations
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Based upon multivariate logistic regression the risk factors associated with Drug Resistance
were patients with hospital acquired UTI, old age, recurrent UTI, diabetes, and previous use
of antibiotics within last three months.
Suggested empirical choice of treatment should be chosen depending on estimates of local
bacterial organisms’ prevalence and antibiotic sensitivities.