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العنوان
Role of positron emission tomographycomputed tomography (PET-CT) imaging in management of hematological malignancies/
المؤلف
Salem, Ahmed Hany Ahmed Ebada.
هيئة الاعداد
باحث / احمد هاني احمد عباده سالم
مناقش / يحي حليم زكي
مناقش / اشرف حسين الغندور
مشرف / جمال الحسيني عطية
الموضوع
Radiodiagnosis. Intervention.
تاريخ النشر
2022.
عدد الصفحات
49 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
9/5/2022
مكان الإجازة
جامعة الاسكندريه - كلية الطب - Radiodiagnosis and Intervention
الفهرس
Only 14 pages are availabe for public view

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Abstract

Early diagnosis of malignant lymphomas is challenging, given the complex nature and
incongruity of these disorders. Compared to B-cell lymphomas (BCLs,) T-cell lymphomas
(TCLs) are relatively rare neoplasms ranging from indolent to aggressive lymphomas and
may be sporadically experienced in clinical practice. Therefore, early diagnosis is challenging
owing to their rarity and the overlap in clinical and imaging features with other more common
disorders.
Imaging in general, and specifically 18F- FDG PET/CT, plays an essential role in the
management of lymphomas. The use of 18F-FDG PET/CT can change the tumor staging in
almost 30% of cases. 18F-FDG PET/CT can impact management by further subclassifying
lymphomas clinically into aggressive or indolent subtypes based on standardized uptake values
(SUVs) and heterogeneity of disease.
Therefore, this study aimed to discuss some rare disorders of TCLs, specifically mature
T-cell lymphomas, including the most common clinicopathologic and imaging features of
each subtype detected by 18F- FDG PET/CT and as well as to give a glimpse of the updates
contained within the new 2016 WHO classification of lymphoid malignancies.
The study describes the clinicopthologic and imaging features observed by 18F-FDG
PET/CT of seven types of uncommon mature T-cell lymphoma disorders.
The first disorder: subcutaneous panniculitis-like T-cell lymphoma, where 18F-FDG
PET/CT help to exclude visceral involvement and delineate the extent of disease for improved
clinical management.