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العنوان
biochemical and molecular studies on the ameliorative role of chitosan against silver nanoparticles induced testicular
/ toxicity and dna damage in male rats
المؤلف
mohamed,aya abd eihakeem saeed
هيئة الاعداد
باحث / آية عبد الحكيم سعيد محمد
مشرف / حامد محمد عبد الباري
مشرف / ايهاب مصطفي طوسون
مشرف / مبروك عبدالدايم
الموضوع
Chemistry
تاريخ النشر
2022
عدد الصفحات
186 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الكيمياء
تاريخ الإجازة
5/4/2022
مكان الإجازة
جامعة المنوفية - كلية العلوم - الكيمياء الحيوية
الفهرس
Only 14 pages are availabe for public view

from 186

from 186

Abstract

6- Summary & Conclusion
Silver nanoparticles (Ag NPs) is one of the most popular nanomaterials have been used in material science, such as one of the constituent elements of dental alloys, catheters, implant surfaces and for treating of wounds and burns related infections, as well as in drug delivery in cancer and retinal therapies. But, there are some concerns about the safety of using Ag NPs in biomedical and in other industries.
One concern is about the probable impacts of Ag NPs on remote organs.
The toxicity of Ag NPs was evaluated by in vivo studies which are shown that these materials may redistribute in different organs and have systemic complications such as weight loss and inflammation.
Theoretically, Ag NPs may have some negative effect on human health and environment and their probable impact(s) on the male reproductive functions is remained to be clarified.
Chitosan is well-known to possess numerous biological activities including anti-diabetic, anti-inflammatory, anti-oxidant, and cholesterol-reducing agents.
However, some properties of chitosan such as water insolubility imped its chemical adaptations, biological, problems may cause the dropping of its biochemical effect and high relative molecular mass, and so nanotechnology is also one among the unique solutions. Chitosan nanoparticles have reported more effectiveness, bio-distribution, reduction of pharmacological toxicity, improvement of the immune effect, antimicrobial and anticancer effects than chitosan itself.