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العنوان
Biochemical and Molecular study on the role of miR-181a and miR-191 as biomarkers for diagnosis of pediatric idiopathic nephrotic Syndrome /
المؤلف
Mersal, Asmaa Mohamed Salah Ibrahim Mabrouk
هيئة الاعداد
باحث / اسماء محمد صلاح ابراهيم مرسال
مشرف / حامد محمد عبد الباري
مناقش / طارق مصطفي محمد
مناقش / جيهان سعيد حسين
الموضوع
MiR181a-5p and MiR191a-5p . MicroRNA .
تاريخ النشر
2022
عدد الصفحات
112 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Organic Chemistry
تاريخ الإجازة
28/3/2022
مكان الإجازة
جامعة المنوفية - كلية العلوم - الكيمياء الحيوية
الفهرس
Only 14 pages are availabe for public view

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from 169

Abstract

Nephrotic syndrome (NS) represents a constellation of symptoms including peripheral edema, heavy proteinuria, hypoalbuminemia, and often hyperlipidemia and is thought to result from increased glomerular permeability to albumin and other plasma proteins (Mahalingasivam et al, 2018). More evidence was reported during the last decade, on the importance of miRNAs in many regulatory mechanisms. MiRNAs are negative post-transcriptional regulators of gene expression and have an important physiological role in a variety of biological processes. Their tissue specificity and stability in biological fluid have been proposed to be potential biomarkers in kidney diseases