الفهرس 
INFLAMMATORY BOWEL DISEASE (IBD)Only 14 pages are availabe for public view
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Abstract
Crohn’s disease (CD) causes transmural ulceration of any section of the gastrointestinal tract (GI), with the terminal ileum and colon being the most commonly affected.
The present study revealed that the mean age of our patients was 54.3± 7.69 years with range from 38-68 years. Male cases were more than females ones, as (70%) were males while (30%) were females, with male to female ratio was 2.33: 1. The present study revealed that the mean hemoglobin level was 11.66 ± 1.46 mg/dl, and the mean RBC, 4.18±0.48. The mean platelets was 267.73±61.94 (K/UL), mean WBCs was 9.94 ± 1.83 (K/UL), neutrophils was 7648.57 ± 1460.02 (/UL), and lymphocytic count was 1356.50 ±469.30 (UL) and neutrophil/ lymphocyte ratio (NLR) was 5.93 ±1.35.
Regarding the renal function tests and electrolyte profile, the mean serum urea, creatinine and uric acid were 46.43-±10.18, 1.10-±0.25 and 5.30-±0.68 mg/dl respectively. The mean levels of Na and K were 140.43 ±3.50 and 3.82±0.26 mEq/L respectively, the mean AST was 37.63 ±8.27 U/L, the mean ALT was 26.30 ±8.36 U/L, the mean total bilirubin was 1.01±0.17 mg/dl and the mean direct bilirubin was 0.60 ±0.27 mg/dl. We found that the mean PT was 14.17±2.65 sec. and the mean Serum Albumin was 4.16 ± 0.29 g/dl. In this study the mean CRP was 4.91 ±4.55, the mean ESR at first was 21.67 ±4.22 and 2nd hour was 47.43±10.94.
Regarding the intestinal ultrasonography findings, the mean BWT was 4.53± 1.66, the mean Bowel wall stratification was found in (70%). Doppler activity: Grade 1 was the commonest between studied cases representing 56.7%. Normal mesenteric fat was found in all cases (100%). Our findings revealed that US predicted patients with CD with accuracy 85%, sensitivity 74.07%, specificity 100%, PPV 100% and NPV 79.4%.
Out of 30 patients, 23 patients considered to be active (77%), and 7 considered to be inactive (23%).
90% of our patients were detected by colonoscopy and 10% were not. The findings were included diffuse ulceration with mucosal hyperemia markedly at recto-sigmoid in 23.3% of the patients, hyperemic mucosa with skip lesions located at sigmoid colon and ileum in 13.3% of the patients, terminal ileitis in 33.3% patients and terminal ileum stricture in 20.0% patients. 80% can be detected by CT and 20% cannot be detected. The findings were included distal ileal long segment of circumferential mural thickening and submucosal edema with adjacent mesenteric congestion in 10% of the patients, recto sigmoid thickening in 23.3% and terminal ilium thickening in 46.7%.The current findings emphasise that, while colonoscopy is the gold standard in CD, US is repeatable, safe, and well-accepted, but unlike CT is radiation-free, and unlike MRI is cheap, virtually hazard-free, and available to all patients without contraindications.