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العنوان
Long term outcomes of percutanous coronary intervention versus coronary artery surgery in elderly with multi-vessel coronary artery disease/
المؤلف
Kandil, Abdel Magied Said Mahmoud.
هيئة الاعداد
باحث / عبد المجيد سعيد محمود قنديل
مناقش / كمال محمود أحمد
مناقش / محمد أحمد صدقة
مشرف / كوكب محمود خضر
الموضوع
Cardiology. Angiology.
تاريخ النشر
2022.
عدد الصفحات
84 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
6/4/2022
مكان الإجازة
جامعة الاسكندريه - كلية الطب - Cardiology and Angiology
الفهرس
Only 14 pages are availabe for public view

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Abstract

Elderly patients with coronary heart disease, have been significantly increasing in number. Cardiovascular disease is the most frequent diagnosis in elderly people, and it is the leading cause of death in both men and women older than 65 years of age. Acute coronary syndrome is responsible for more than 30% of mortality causes in elderly population. The rate of growth of the older segment of the population has increased exponentially and will become more pronounced in the future. Historically, physicians are prone to more conservative treatment and use less aggressive therapies, however, elderly patients are more likely to complications, owing to age related physiological changes and age comorbidity. The comparison of coronary artery bypass graft surgery and percutaneous intervention for treatment of patients with multi-vessel disease with or without distal left main coronary artery disease remain still debated.
Many studies proved that cardiovascular mortality was significantly lower in PCI and CABG than the medical treatment, but there is lack of clinical trials investigating the challenges, outcomes and prognosis of more invasive treatment strategies such as PCI in elderly in stable coronary artery disease due to several factors as complexity of coronary lesions, hematological and vascular changes.
The balancing risks and benefits of revascularization in elderly patients with multi-vessel coronary artery disease is a challenge and the appropriate revascularization strategy is unclear. Other studies showed that there is no significant difference between PCI and CABG in elderly patients with multi-vessel disease in mortality. The best option in coronary revascularization of elderly patients is largely unknown. Although there are many clinical studies and assessment system about indication and contraindication of revascularization, targeted studies and point scoring system in elderly patients are relatively absent, however our country and international community are facing aging of population, associated with increased morbidity of elderly CHD patients. Thus, it is necessary to enhance our knowledge about the outcome of the retrospective study of PCI versus CABG in elderly patients to provide targeted assessment system for elderly CHD patients.