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العنوان
Effect of Argel Herbs (Solenostemma argel) on-induced Liver Cirrhosis by Carbon Tetra Chloride in Rats \
المؤلف
Saman, Dalia Demian Azer.
هيئة الاعداد
باحث / داليا دميان عازر سمعان
مشرف / ايمن فتحي خليل
مشرف / اسحق مراد الحديدي
مشرف / الشيماءعبد الله حافظ
تاريخ النشر
2022.
عدد الصفحات
110 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
اقتصاد منزلي
تاريخ الإجازة
1/1/2022
مكان الإجازة
جامعة عين شمس - كلية التربية النوعية - الاقتصاد المنزلي
الفهرس
Only 14 pages are availabe for public view

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Abstract

Argel (Solenostemma argel) is a traditional edible herb that is commonly used in folkloric medicine for the treatment of rheumatic pain, inflammation, hyperlipidemia, hyperglycemia and antimicrobial agent due to its rich in bioactive component which act as antioxidants. Dried leaves Argel had a high content of carbohydrate and protein (76.19 and 14.10 g/100g on dry weight) respectively. Manganism were higher contents in Argel (98.40 mg/g) dry weight basis, repsctively than zinc and copper (4.40 and 10.0 mg/g, respectively).
Forty-eight male albino rats were used in biological experiments. Rats were fed the basal diet for two weeks prior to conducting the experiment. Initially, rats divided into six main groups and fed on rations for 42 days as follows: the negative control group (the first group) was fed on the basal diet. Forty male albino rats were fed on a basic diet and stimulated with carbon tetra chloride (CCl4( in paraffin oil (50% v/v, 2 mL/Kg) twice a week by subcutaneous injection to induce chronic liver damage, then divided into5 groups numbered from group 2 to group 6. Rats of the positive control group were fed basal diet until the final experiment. group 3 and 4 rats were treated with dry leaves (0.5g and 1.0g, respectively) of Argel. Also, group 5 and 6 were fed on 50 ppm and 100 ppm of hydroethanolic extracts orally, respectively.
Biochemical analyses as serum ALT, AST, ALP and MDA were significant decreased in rats fed on dried and extracts in Argel compared to positive group. In Contrast, it could be that SOD activity in rat groups was significant increased compared to positive group. Also, Argel extracts had highest effect for liver parameters than dried Argel.
The best results of taste evaluation were in Kiwi pulp samples fortified with 50ppm and 100ppm argel water extract, then 50ppm, 100ppm argel ethanolic extracts, the values no significant difference between them (8.42, 7.50, 8.00 and 8.17, respectively) compared to control (8.42). At the same trend, results showed that no significant difference in odor (8.58, 8.83, 8.25, and 8.25, respectively) and color (8.92, 8.58, 8.25, and 8.83, repsictively) parameters in different groups.
These results are concluded that Argel could be suggested to the hepatoprotective effect of Argel may be due to its antioxidants content and free radical scavenging effect.