الفهرس 
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Abstract
Klebsiella pneumoniae is regarded globally by the World Health Organization (WHO) as a priority antimicrobial-resistant pathogen requiring new control strategies due to its ability to accumulate multiclass antibiotic resistance determinants over time in addition to causing severe community- and hospital-associated infections. Besides, K. pneumoniae possesses different virulence factors that contribute to its pathogenicity including lipopolysaccharide (LPS) O-side chain (endotoxin), capsular polysaccharide, adhesions (fimbiriae) and sidrophores.
This study aimed to detect some virulence genes in clinical isolates of K.pneumoniae isolated from patients of sepsis in SCUHs in Ismailia in addition to evaluating the association between the presence of these virulence genes and the clinical outcome of those patients.
A total of 146 specimens were collected from patients with sepsis admitted in different wards in SCUHs, from which a 49 Klebsiella pneumoniae strains were isolated (33.6%). The highest percentage of K. pneumoniae isolates were from the ICU department (46.9%) followed by the NICU department (24.5%). Also, the highest percentage of K. pneumoniae was isolated from endotracheal aspirates (ET) (28.6%), followed by sputum (22.4%), then blood (20.4%).
Antimicrobial resistance pattern of the isolated strains showed that