الفهرس | Only 14 pages are availabe for public view |
Abstract Statistical analysis revealed the following: • There was no statistically significant difference found between two groups regarding Age, Sex and BMI, and there was Highly statistically significant difference found between two groups regarding APATCHEII Score and SOFA Score. • There was no statistically significant difference found between two groups regarding DM, HTN, Smoking. • There was no statistically significant difference found between two groups regarding HB, Creatinine, Urea, ALT, AST, Albumin (g/dL) (mEq/L), K, Ca, CL (mEq/L) and HCO3 (mEq/L), and there was highly statistically significant difference found between two groups regarding Wbcs, and there was statistically significant difference found between two groups regarding Na (mEq/L) and Platelet. • There was Highly statistically significant difference found between two groups regarding need of Mechanical ventilation. • There was no statistically significant difference found between two groups regarding Complications. • There was no statistically significant difference found between two groups regarding Icu LOS (days). • There was no statistically significant difference found between two groups regarding Serum lactate arterial 1st, Serum lactate arterial 2nd, Serum lactate venous 1st, Serum lactate venous 2nd, Base deficit arterial 1st, Base deficit venous 1st and there was highly statistically significant difference found between two groups regarding Base deficit arterial 2nd and base deficit venous 2nd. • There was statically significant Positive correlation between Serum lactate arterial 1st and Serum lactate venous 1st. • There was statically significant Positive correlation Serum lactate arterial 2nd and Serum lactate venous 2nd. • Therer was strong correlation between lactate and base excess • But not with anion gap. Conclusion O ur study demonstrated a high level of agreement in the lactate levels as measured on venous samples and arterial samples in patients with septic syndrome; we also demonstrated that lactate and base excess showed a strong correlation with each other, but not with anion gap. Thus, these biomarkers can be used interchangeably to help in the early determination of septic shock, and also venous lactate levels are reliable in the resuscitation of patients with sepsis. A larger multicenter study may be required to confirm the generalizability of our results. |