الفهرس | Only 14 pages are availabe for public view |
Abstract Background: Nonalcoholic fatty liver disease (NAFLD) is independently linked to cardio-metabolic morbidity and mortality. Low-grade inflammation, oxidative stress and ectopic fat, common features of chronic obstructive pulmonary disease (COPD), might contribute to the development of NAFLD. Aim and objectives: The aim of the study was to determine the possible association between chronic Obstructive Lung Disease and Non-Alcoholic Fatty Liver Disease. Subjects and methods: This was a cross sectional study, which was carried out at Outpatient Clinics at Ain Shams Hospital, 60 Egyptian Patients divided into two groups: group 1:40 Patients diagnosed with COPD (Patients diagnosed by history of disease, smoking history and A ration of post bronchodilator FEV1 10 FVC of less than 70% of the predicted value) and group 2: 20 Normal Healthy People (Control Group). Results: there was a statistical significant difference with p-value <0.05 between study groups as regards spirometry with low mean FEV1, FVC , and FEV1/ FVC ratio among cases. Conclusion: NAFLD is associated with COPD. Physicians should be aware of possible liver comorbidities in COPD patients and that extra-hepatic disease in NAFLD patients may vary more than previously thought. |