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العنوان
FDG PET/CT in Follow UP Patients with Colorectal Carcinoma after Adjuvant Chemotherapy/
الناشر
Ain Shams University.
المؤلف
Elbastawessy ,Rafik Abdelazim .
هيئة الاعداد
باحث / رفيق عبدالعظيم البسطويسي
مشرف / هناء عبدالقادرعبدالمجيد
مشرف / ريمون زاهر ايليا
مشرف / أحمد محمد بسيوني
تاريخ النشر
2022
عدد الصفحات
177.p;
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/1/2022
مكان الإجازة
جامعة عين شمس - كلية الطب - Diagnostic Radiology
الفهرس
Only 14 pages are availabe for public view

from 177

from 177

Abstract

ABSTRACT
Background: 18F-2-fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography-computed tomography (PET-CT) is a type of imaging that evaluates and quantifies metabolic avidity in cancer cells, acting as a surrogate for the underlying cellular activity and vitality, and so providing anatomic and metabolic data. In patients with colorectal cancer, 18F-FDG PET-CT is useful for detecting local recurrence, distant metastases, and assessing tumour vitality after chemotherapy and radiotherapy. To achieve the best results, strict adherence to defined protocols, technical processes, and good patient preparation are required. The study aimed to evaluate the role of PET/CT in follow up patients with resected colorectal carcinoma and finished cycles of adjuvant chemotherapy.
Results: In our study, PET/CT early detected hepatic deposits, pulmonary masses, bone deposits, and sizable LNs. PET/CT provided useful information and had a considerable impact on disease management, enabling the detection of recurrent disease as early as possible with high accuracy in assessment of therapeutic response. It detected viable residual tumor cells in operative bed scar, small metabolically active LNs, hepatic focal lesions, peritoneal deposits, pulmonary secondaries, and bone deposits avoiding unnecessary surgeries.
Conclusion: FDG-PET-CT imaging is useful to evaluate post-therapeutic colorectal cancer patients with suspected tumor recurrence or distant metastasis largely because of its high accuracy in detection and its ability to characterize recurrent disease.