الفهرس 
MATERIALS AND METHODSOnly 14 pages are availabe for public view
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Abstract
This randomized controlled clinical trial was conducted to evaluate the clinical and radiographic outcomes of Chitosan scaffold and Mineral trioxide aggregate (MTA) when used as pulpotomy agents in mature permanent teeth with irreversibly inflamed pulps.
A chitosan membrane was fabricated using the freeze-gelation method. The tailored membrane was sterilized by Ethelene oxide and was then characterized by scanning electron microscope (SEM), X-ray diffraction (XRD) and Fourier transform infrared (FTIR) spectroscopy. The rate of degradation and the PH of the developed scaffolds were in-vitro calculated over a period of 4 weeks.
A full pulpotomy procedure was carried out in thirty mandibular permanent molars in patients with age ranged between 19-38 years old and with clinical signs and symptoms indicative of irreversible pulpitis. After the control of bleeding with a cotton moistened with 2.5% NaOCl, the teeth were randomly allocated into two groups according to the pulp dressing material; group I (control group) received MTA pulp dressing material, and group II received chitosan membrane followed by MTA. The teeth were then restored with a base of Glass ionomer cement followed by composite restoration.
All patients were recalled after one week to check the postoperative pain recorded by the patient on the Numerical Rating Pain Scale (NRS). The patients were then clinically and radiographically assessed for any signs and symptoms of pathosis at 1,3,6,9 and 12 months. Cone beam computed tomography (CBCT) analysis was done immediate post operatively and after 12 months to evaluate the amount of dentin bridge formed under the pulp dressing material and to assess the periapical health.