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Abstract Summary Introduction Diabetic retinopathy (DR) is considered the most common cause of blindness in working age group especially proliferative diabetic retinopathy (PDR). PDR can cause significant visual impairment secondary to vitreous hemorrhage or tractional retinal detachment.(1),(2) The pioneers in retinal diseases used to diagnose diabetic retinopathy using color fundus photos and fluorescein angiography as it was considered the main approach to evaluate retinal vasculature. Optical coherence tomography can capture high quality retinal cut sectional images to evaluate retinal structure and its applications have grown remarkably over years. (3) Recently, Optical coherence tomography angiography (OCTA), non-invasively- can evaluate retinal and choroidal vasculature.(4) OCTA may potentially facilitate staging of DR or even detection of early DR changes prior to clinically detectable retinopathy.(11) Thus, it shows promise in supplementing clinical examination by potentially replacing fluorescein angiography (FA) for the diagnosis and monitoring of DR. Until recently, this was not achievable due to the limited field of view of earlier devices. However, widefield OCTA (WF-OCTA) device has become available, allowing for montaging of several scans in real-time, thus providing almost 80 degrees’ field of view in a single scan.(12),(13) Aim of the work The aim of this work is to characterize the use of widefield Optical Coherence Tomography Angiography (WF-OCTA) in patients with diabetic retinopathy and to compare clinical examination and Ultrawidefield Fluorescein Angiography (UWF-FA), when available, with widefield Optical Coherence Tomography Angiography (WF-OCTA) in grading diabetic retinopathy. |