الفهرس | Only 14 pages are availabe for public view |
Abstract Epilepsy is one of the most common neurologic problems worldwide. According to research, 3 per cent of persons in the general population will have epilepsy at some point in their lives. Approximately, 724,500 people with epilepsy live in the Arab world. Juvenile myoclonic epilepsy (JME) is a common epilepsy syndrome that is classified as one of the idiopathic generalized epilepsies (IGEs). It includes a group of seizure patterns that are clinically distinct from those in other forms of IGE, with the major characteristic being adolescence-onset myoclonic seizures. Although the pathogenesis is not clearly understood, several possible mechanisms are suggested. The relationship between obesity and epilepsy is a rich and interesting area for research. There are potential reasons to consider that patients with epilepsy have a higher risk of developing obesity than the general population. First, epilepsy itself may cause progressive weight gain through central nervous system (CNS) pathways. Second, bodyweight gain is a known common and frequent undesirable effect associated with the use of antiepileptic drugs. This has been observed for many years with valproic acid (sodium valproate) and carbamazepine, and also, more recently, with some of the newer antiepileptics such as vigabatrin and gabapentin. Finally, some studies have found that patients with epilepsy participate less frequently in physical activities than the general population. This restriction has been explained, partly due to fears of either injury during seizures or the possibility of exercise-induced seizures. |