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Abstract This study concluded that the use of the nanofiltration in the seawater application is possible and that was clear from the WAVE software simulation and the corresponding recorded data from the experimental results. That proved the nanofiltration could be used in the seawater salinity range from 10000 ppm to 40000 ppm. While the feed temperature affects the permeate TDS, the feed pressure and the membranes salt rejection. And the relation between the feed temperature and both the feed pressure and the salt rejection is inverse relationship while the relation between the feed temperature and the permeate salinity is positive relationship |