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Abstract Summary - 59 - Summary This randomized comparative study was performed at cardiothoracic surgery department at Menoufia University from May 2018 to December 2020. Sixty patients having coronary artery disease were subjected to CABG surgery. The Patients were randomly allocated according to the preoperative use of aspirin into two groups 32 patients in group (A) received 100 mg enteric coated aspirin per day until the day of surgery and 28 patients in group (B) received aspirin 100 mg daily until 5 days before surgery. To evaluate the effect of duration of preoperative aspirin cessation on perioperative morbidity in patients undergoing CABG surgery: all patients were evaluated thoroughly preoperative, intra-operative and postoperative, especially the duration of mechanical ventilation, use of inotropes, ICU stay and 30 days morbidity and mortality. Results: The results of our research showed that the late use of Aspirin till the day of surgery is associated with less ICU stay and earlier weaning from mechanical ventilation, while there was no statistically significant difference in bleeding, blood transfusion and reoperation for bleeding in the late use of Aspirin. There was also no difference in postoperative MI or 30 days all-cause mortality. |