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العنوان
The role of the conserved microtubule regulator Stathmin in structural maintenance of sensory neurons in Drosophila melanogaster =
المؤلف
Hemdan, Fatma Ibrahim Elshabrawi Ali.
هيئة الاعداد
مشرف / Fatma Ibrahim Elshabrawi Ali Hemdan
مشرف / Amina Essawy Essawy
مشرف / Mourad L. Shonouda
مشرف / Peter Soba
الموضوع
Neuroscience. Biotechnology.
تاريخ النشر
2019.
عدد الصفحات
102 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Multidisciplinary تعددية التخصصات
تاريخ الإجازة
9/6/2019
مكان الإجازة
جامعة الاسكندريه - كلية العلوم - Neuroscience and Biotechnology
الفهرس
Only 14 pages are availabe for public view

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Abstract

Proper development of dendrites is important for connectivity and functional neuronal network. By studying development of class IV dendritic arborization neurons in Drosophila melanogaster it was found that Stathmin, conserved microtubule destabilizing protein, is crucial for C4da proper morphogenesis in the posterior segment of larvae. Knock-out of Stai gene cause degeneration of the neurons in the posterior segments of the larvae and the dendritic phenotype was rescued completely with D-staiB2, partially with h-stmn2, and no rescue at all with D-staiA1.