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العنوان
Optical Coherence Tomography Angiography
Changes in The Fellow Eye of Unilateral Primary
Congenital Glaucoma /
المؤلف
Saad، Sarah Abd El-Fattah.
هيئة الاعداد
مشرف / ساره عبد الفتاح سعد
مشرف / محمود أحمد كمال
مشرف / غادة إسماعيل جودت
مشرف / ياسمين محمد السيد
الموضوع
qrmak
تاريخ النشر
2021
عدد الصفحات
99 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
طب العيون
تاريخ الإجازة
8/2/2021
مكان الإجازة
جامعة الفيوم - كلية الطب - طب وجراحة العيون
الفهرس
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Abstract

Purpose; To study the fellow eye of unilateral congenital glaucoma (PCG) patients
with optical coherence tomography angiography (OCT-A), comparing them to the
normal age-matched controls.
Design; prospective cross-sectional study.
Patients and Methods; Thirty two cases with unilateral congenital glaucoma in
group A and 32 normal controls in group B were recruited in the study with age 4 –
14 years old. Both groups were investigated by OCT-A comparing Foveal
avascular zone (FAZ) area, Central macular thickness (CMT), Cup to disc (CD)
ratio, Retinal nerve fiber layer (RNFL) thickness, Choroidal thickness (CT), Vessel
density (VD) in the Superficial vascular complex (SVC) and Deep vascular
complex (DVC) in both 3mm and 6 mm scans.
Results; Sixty four eyes were included in the study with age range 4-14 years for
both groups. Equal sex distribution in group B, while group A had 22 (68.8%)
males. The CD ratio was higher in group A compared to group B (range 0.13±0.14
in A and 0.07±0.09 in B p-value 0.039). Mean RNFL thickness was 113.81±15.4
µm and 117.41±13.19 µm in group A and B respectively. Mean CT in group A was
396.81±39.98 µm and 375.34±41.72 µm in group B (P-value 0.04). Mean CMT
was 235.69±17.96 in group A and 234.16±15.2 in group B. The FAZ area was
smaller in group A (0.3± 0.1mm 2 ) than group B (0.35±0.13mm 2 ) (p-value 0.093).
The VD at fovea in group A in 3mm scan was (19.41±6.88%) and group B was
(15.95±5.87%) (p-value 0.034). The VD in the superficial whole image in 6mm
scan was lesser in group A (49.42±2.58%) than group B (50.74±2.6%) (p-value
0.045). Both cases and controls were not significantly different regarding the VD
at the disc area.
Conclusion; The fellow eye of unilateral PCG cases are not entirely normal with
less vascular density by OCT-A and needs long term follow up.