الفهرس | Only 14 pages are availabe for public view |
Abstract Meningitis is an inflammation of the meninges and subarachnoid space that can also involve the brain cortex and parenchyma owing to the close anatomical relationship between the cerebrospinal fluid (CSF) and the brain. Meningitis was classified according to etiology into two major categories infectious and non-infectious. The infectious group including bacterial, viral, spirochetal, fungal and parasitic causes, while the non-infectious causes involve the subarachnoid hemorrhage, collagen diseases, neoplasms, and drugs. Although acute meningitis particularly in children is mainly aseptic (viral), bacterial meningitis is a severe infection of the central nervous system which occurs especially in children <5 years of age. This study aimed to evaluate the clinical importance of interleukin 8 in cerebrospinal fluid as a marker in children with acute bacterial and aseptic meningitis. Patients and methods This is a prospective cohort study conducted on 80 children of both sexes who were diagnosed with acute meningitis and admitted to Meit khalf fever hospitals from May 2019 to January 2020. Inclusion criteria: Age: 2months-15 years, Sex: both sexes, Children with acute bacterial meningitis whose criteria of selection was based on (Straus and Thorpe 2012). Children with viral meningitis: criteria for viral meningitis include an increase in WBCs from 5 to 100 cells/ mm³ with a predominance of lymphocytes based on. |