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Abstract Psoriatic arthritis (PsA) is a chronic, immune mediated, inflammatory musculoskeletal disease characterized by inflammation of not only articular sites but also extra articular sites like entheses, tendons, fingers, toes and skin, associated with several comorbidities. PsA was identified as a separate form of inflammatory arthritis but under the term of seronegative spondyloarthritis. Pain is a major concern for patients with PsA having a significant clinical, economic and social burden. It may be a nociceptive type of pain (caused by the inflammatory damage and tissue destruction), a neuropathic (due to augmented central pain processing) or even mixed type may be present. The different pain mechanisms in PsA patients may lead to misinterpretation of disease activity and excessive immunosuppressive therapy that may be harmful. Ultrasound (US) is a highly sensitive method to detect tissue inflammation in PsA, so it adds to accuracy of disease activity measurement. The aim of this study is to determine the relation between pain severity and pain components parameters and inflammatory disease activity by clinical and US scores. |