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العنوان
Dermoscopic and Histopathological Findings in Psoriasis before and after Treatment /
المؤلف
Essawy, Dalia Mohamed Mahmoud Mohamed.
هيئة الاعداد
باحث / داليا محمد محمود محمد عيسوى
مشرف / أمل طلعت عبدالرحمن عبدالحليم
مشرف / محمد أحمد محمد عبدالمجيد الخياط
الموضوع
Psoriasis.
تاريخ النشر
2021.
عدد الصفحات
148 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأمراض الجلدية
تاريخ الإجازة
1/1/2021
مكان الإجازة
جامعة المنيا - كلية الطب - الأمراض الجلدية والتناسلية
الفهرس
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Abstract

Background: Psoriasis is a chronic and inflammatory skin disease. Few studies in the literature evaluated the responses to the treatment dermoscopically and histopathologically.
Aim and objectives: the aim of the study was to evaluate and to compare the dermoscopic and histopathological findings in patients with psoriasis lesions before and after treatments with corticosteroids and with narrow band ultraviolet rays (UVB).
Subjects and methods:this study was a prospective comparative study that was conducted on 30 patients with psoriasis randomly divided into two equal groups; group I: included 15 patients having narrow band (UVB) sessions twice weekly, while group II: included 15 patients having topical Elcon (Mometasone furoate) ointment twice daily.
Results: the results revealed that mean ± SD. of PASI score before treatment in group I was 23.43 ± 8.09 and in group II was17.70 ± 7.40 with no statistically significant difference between the two groups as regard PASI score before & after treatment in group I. In group II, there was a high statistically significant difference between before and after treatment as regard PASI score. The dermoscopic and histopathological changes showed a significant improvement after treatment in both groups.
Conclusion: Both narrow band ultraviolet B (NB-UVB) and corticosteroids affect the PASI score significantly with improvement of the dermoscopic and histopathological changes. These improvementswere more predominant in patients treated with NB-UVB.