الفهرس 
EPIDEMIOLOGY OF UPJOOnly 14 pages are availabe for public view
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Abstract
UPJO is the most common congenital abnormity of the upper urinary tract. The goal of surgical intervention in patients with UPJO is to improve urinary drainage from the dilated collection system and prevent deterioration of renal function as well.
The main diagnostic investigations are: ultrasound, and diuretic renogram. The sensitivity of ultrasound in the diagnosis of obstruction can be enhanced by including an assessment of the renal hydronephrosis area & parenchymal thickness (PHAR), with the main advantages of ultrasound are ease of use, high patient tolerance, non-invasiveness, lack of ionizing radiation, low relative cost, and wide availability unlike other investigations.
We enrolled 36 cases of children ≤ 16 years old (7.93 ± 0.83) with unilateral UPJO. Preoperative ultrasound parameters of the hydronephrotic kidneys [including degree of hydronephrosis, parenchymal thickness and PHAR] and renal isotope are measured & compared with the same parameters after surgical repair of the UPJO (Anderson Hynes pyeloplasty) at 3rd months.
We find a significant change in all parameters at 3 months postoperatively (p < 0.01) as T ½ (25.22 ± 2.49 & 17.57 ± 3.84) significantly decrease & parenchymal thickness (9.42 ± 4.92 & 15.12 ± 4.86), GFR of the affected kidney (34.31 ± 3.31 & 48.32 ± 6.99) split renal function (37.30 ± 3.80 & 44.03 ±4.11) and PHAR (0.86 ± 0.30 & 2.45 ± 0.93) significantly increase post operatively.
PHAR post operatively shows positive correlation with parenchymal thickness & renal isotope while negative correlation with T ½.