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العنوان
لThe efficacy of a single intraoperative dose of intravenous dexamethasone in post-caesarean delivery analgesia/
المؤلف
Elseidy, Hadeer Salah Ahmed Mohamed.
هيئة الاعداد
باحث / هدير صلاح أحمد محمد الصعيدى
مشرف / سلوى شعبان شعراوي
مشرف / أحمد منصور أحمد
مشرف / عمرو محمد حلمي زكي
الموضوع
Anaesthesia . Surgical Intensive Care.
تاريخ النشر
2021.
عدد الصفحات
p67. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب
تاريخ الإجازة
14/10/2019
مكان الإجازة
جامعة الاسكندريه - كلية الطب - Anaesthesia and Surgical Intensive Care
الفهرس
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Abstract

Caesarean delivery rates are increasing worldwide, and effective postoperative pain management is a key priority of women undergoing caesarean delivery. Inadequate pain management in the acute postoperative period is associated with persistent pain, greater opioid use, delayed functional recovery, and increased postpartum depression. (5)
The majority of caesarean section deliveries are typically approached with a single-dose spinal anaesthetic technique. In cases where the obstetrician expects the length of the procedure to go beyond 2 hours, a neuraxial catheter-based technique (epidural or combined spinal–epidural) may be utilized. In the absence of contraindication to neuraxial anaesthesia, it is rare that general anaesthesia is induced for an elective Caesarean delivery in most developed countries. (7)
Dexamethasone, a glucocorticoid, is commonly administered in the peri-operative period for its proven antiemetic effect. It also has anti-inflammatory, analgesic, and antipyretic effects, which may be beneficial in the management of post-caesarean pain, nausea and vomiting.
The aim of the present study was to assess the efficacy of a single intraoperative dose of intravenous dexamethasone in post-caesarean delivery analgesia as well as patients’ haemodynamics, total dose of analgesic drugs, postoperative nausea and vomiting and post spinal shivering.
The present study was carried out in El Shatby University Hospital on 50 patients, aged 18 to 35 years, with American Society of Anesthesiologists (ASA) physical status II, at term gestation (≥37 weeks’ gestational age) and scheduled for caesarean delivery under spinal anaesthesia.
Patients were randomly assigned into two equal groups 25 each using closed envelope technique:
• group (A): Received single dose of 8mg intravenous dexamethasone “2ml volume”.
• group (B): Received 2ml of normal saline (0.9%) as a placebo.
In operating theater. A multichannel monitor was connected to the patients to display Continuous Electrocardiography monitoring for heart rate (beat/min), NABP and (SpO2%).
All patients were preloaded with 10 ml/kg normal saline (0.9%). Subarachnoid block was achieved in the sitting position using Quincke spinal needle (25G) introduced in the L2-L3 or L3-L4 intervertebral space, 2.5 ml of hyperbaric bupivacaine (0.5%) was injected, and surgery commenced after achi