الفهرس 
Aim of the studyOnly 14 pages are availabe for public view
 |  | from | 133 |  |  |
| | | from | 133 | | |
Abstract
Systemic lupus erythematosus is a chronic, multisystemic, inflammatory, autoimmune disorders characterized by formation of autoantibodies directed against self-antigen and immune complex resulting in wide range of clinical manifestations and target organs (kidney, lungs …) damage with unpredictable flares and remissions that eventually lead to permanent injury.
Lupus nephritis (LN) is one of the severe manifestations of systemic lupus erythematous (SLE) and a common cause for end-stage renal disease significantly affecting the survival of SLE patients.
This is a retrospective observational study conducted to determine the predictors of remission in lupus nephritis patients,and to assess the long-term renal remission rate in our Lupus nephritis patients.
The study included 60 SLE patients with biopsy-proven LN were identified and categorized into remission group ( partial or complete ) and no remission group :
group 1: with remission included 19 SLE patients with partial remission and 25 SLE patients with complete remission.
group 2: with no remission included 16 SLE patients with biopsy proven lupus nephritis with no response.
The obtained data revealed that,
The UPCR of≤4.9 g/g, SLEDAI of ≤20 & Hb of >8.8 g/dl at the third month are valuable for predicting remission at the sixth month in active Lupus Nephritis.
However, Serum creatinine level ≤2.9 mg/dL at the time of diagnosis was the only independent predictor of remission at 6