الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Prior to the identification of H. pylori, studies demonstrated a
greater incidence of COPD and tuberculosis in patients with peptic ulcers
compared with the general population.
Research has suggested a potential mechanism of the relationship
between H. pylori and pulmonary diseases. Since H. pylori is a Gramnegative
bacterium, lipopolysaccharide is one of the main compositions
of its wall, which stimulates production of proinflammatory cytokines,
such as interferon alpha, and interleukins 1, 2, and 8, leading to chronic
inflammation, stimulation of the immune system, and cancer.
We conducted this case control study to assess relationship
between H. pylori infection and different pulmonary disease on 60
subjects at Chest Department Menoufia University hospital divided to six
groups, group I included 10 COPD patient, group II included 10
asthmatic patient, group III included 10 patient with interstitial lung
disease, group IV included 10 patient with bronchiectasis, group V 10
patient with malignancy and group IV included 10 healthy control
subjects.
All patients subjected to full history, general and local examination
of the chest, radiological investigation in the form of chest x ray(PA –
Lateral ) and CT if needed, immunoassay to measure immunoglobulin G
(Ig-G) antibody titer in serum sample and spirometry with reversibility
tests including (FEV1, FVC, FEV1 /FVC, FEV 25-75% & MVV) .
Pathological examination were done to lung biopsy taken from malignant
group