الفهرس 
المقدمةOnly 14 pages are availabe for public view
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Abstract
The research effort to understand NK cell biology in terms of function and its role of their receptor interactions. Their task in attacking tumor cells is now well established. However, a clearer picture to determine their specific roles in diseases such as asthma, diabetes and rheumatoid arthritis is still desired.
The NK cell plays a major role in human health and disease. Although persistent abnormalities in NK cell activity or number appear to be associated with a wide spectrum of human diseases, evidence for the causal association of abnormally low NK activity with pathogenesis is so far available only from a limited number of experimental models.
For diseases characterized by NK cell deficiency, therapy with adoptively transferred purified and in vitro-activated subsets of NK cells or with BRMs, which can restore or augment NK activity in vivo, offers an opportunity to demonstrate that the NK cell contributes to immunopathogenesis.
Further investigation is required to understand the interactions of NK cells with other cells of the immune system such as T cells, dendritic cells and macrophages. But there is no doubt that NK cells will emerge as major players in the area of cancer treatments, viral infections, including HIV/AIDS, autoimmune diseases and asthma in the coming decade.
The immediate future may see the use of NK cell therapy in combination with chemotherapy, radiotherapyand surgery for cancer. More focus should be placed on establishing techniques for the isolation and expansion of these cells in their required numbers.